Glucosamine Sulphate 2KCl is the basic building block of all cartilage, ligaments, tendons, and joint fluid which is vital for joint health. It is the highest quality and most bio-available form of Glucosamine on the market. The 2KCl is Potassium Salt, which most mammals are deficient in, will benefit from, and their body will readily use; which helps make our formula even more bio-available. We use a very specific ratio of glucosamine to sulfate to potassium… which is tested every single batch, and allows our products to remain consistent and of the highest quality for nearly a quarter of a century. NACl = SODIUM Salt, which nearly every single body, other than those under oxidative stress or sweating along, get more than enough sodium in their diet, which can make absorption and use or any nutrients combined with that more difficult to use, and more likely to pass through the system.

MSM (methyl sulfonyl methane) supplies biologically active sulfur, which is required to build joint cartilage and connective tissues & improves lubrication. There are only 6 companies in the entire world that manufacture MSM, only a couple that is the only product they make. The type we use is the absolute best, from a company that originally discovered MSM nearly 33 years ago, and holds 26 human patents, and 26 animal patents, on process, function, use, and many peer reviewed clinical trials over the years to back up their claims. Dr. Bergstrom was a pioneer in the field of nutrition and bio-availability.

Manganese AAC (Amino Acid Chelate) is the most concentrated, and bio-available for, discovered decades ago by Albion Labs. Manganese has been found to be essential in the formation of skeletal cartilage and is require in the biological chemicals that use Glucosamine.

Ascorbate (vitamin C) is used in this product for ingredient stability and to increase product shelf life. Most all animals, except human beings, many in the ape family and guinea pigs, produce all the ascorbic acid their body needs, in the liver from glucose, from today’s modern diets. Most mammals that have a normal steady diet get most all of the vitamin c they need, with those few exceptions; unless they have an immune deficiency, liver dysfunction, or prolonged oxidative stress.

The MD’s Choice Joint Supplements DO NOT contain Chondroitin Sulphate. Never have and never will; because, studies have show that when taken orally, only 10% to 30% of Chondroitin Sulphate is absorbed, and only a fraction is actually used by the body. Whereas up to 98% of the MD’s Choice joint formula is actually absorbed within 30 to 45 minutes, and can be found in the joint tissue within 4 to 6 hours. No product with chondroitin can honestly say either of those things.

The MD’s Choice products do NOT contain: CetylM (CetylMeristoloate). Cetylated fatty acids are a group of naturally occurring fats. They include cetyl myristoleate, cetyl myristate, cetyl palmitoleate, cetyl laureate, cetyl palmitate, and cetyl oleate. Cetyl myristoleate usually receives the most attention in joint products, because it has shown to block pain or inhibit some symptoms. Many products that contain cetyl myristoleate also contain a mixture of these other cetylated fatty acids at varying levels, that are often inconsistent from batch to batch. IT DOES NOT HEAL, HELP HEAL, or PROMOTE HEALING! But this ingredient may act as a symptom blocker or reduce pain for some bodies.

The doctors that founded MD’s Choice strongly believe that pain killers have their place, benefit, and need… but should be used AS NEEDED, when needed, and under no circumstances belong in a daily supplement intended for prolonged use.
MD’s Choice products do NOT contain Oral H A (Hyaluronic acid, which is also known as hyaluronate, also called hyaluronan, and is an anionic, nonsulfated glycosaminoglycan), or any other painkiller.

Another important scientific note: Hyaluronic acid is also a component of the group A streptococcal extracellular capsule, and is believed to play a role in virulence. (Just wrap your head around that one, there are many interesting studies on the topic).

Next, Hyaluronic acid is also a major component of skin, where it is involved in tissue repair. When skin is exposed to excessive UVB rays, it becomes inflamed (sunburn) and the cells in the dermis stop producing as much hyaluronan, and increase the rate of its degradation. Hyaluronan degradation products (remainders) accumulate in the skin after UV exposure. Further, in some cancers, hyaluronic acid levels correlate well with malignancy and poor prognosis. Hyaluronic acid is, thus, often used as a tumor marker for prostate and breast cancer. It may also be used to monitor the progression of the disease. The various types of molecules that interact with hyaluronan can contribute to many of the stages of cancer metastasis, i.e. further the spread of cancer. Hyaluronic Acid Synthases (HAS) play roles in all of the stages of cancer metastasis. By producing anti-adhesive HA, HAS can allow tumor cells to release from the primary tumor mass, and if HA associates with receptors such as CD44, the activation of Rho GTPases can promote epithelial-mesenchymal transition (EMT) of the cancer cells. During the processes of intravasation or extravasation, the interaction of HAS produced HA with receptors, such as CD44 or RHAMM, promote cell changes that allow for the cancer cells to infiltrate the vascular or lymphatic systems.
Finally, in the formation of a metastatic lesion, HAS produces HA to allow the cancer cell to interact with native cells at the secondary site and to produce a tumor for itself. (Bharadwaj AG, Kovar JL, Loughman E, Elowsky C, Oakley GG, Simpson MA (2009). “Spontaneous metastasis of prostate cancer is promoted by excess hyaluronan synthesis and processing”. Am. J. Pathol. 174 (3): 1027–36. PMC 2665762 Freely accessible. PMID 19218337. doi:10.2353/ajpath.2009.080501)
The MD’s Choice joint products are also guaranteed to work more effectively than liquids. However, the MD’s Choice products do NOT HAVE any of the herbal pain killers, masking agents, and symptom blockers all the liquids we’ve seen the ingredient list to thus far… which their manufactures claim ‘work,’ are actually filled with. You can learn much more about that at: – where just your email address will gain you access to a link of over 40 pages of “Joint Supplements: The Good, Bad, and Useless” (a list of ingredients commonly found in joint supplements sold in the USA and other countries, and what they actually do within a body).

Remember, just because they ‘appear’ to be in less pain does NOT MEAN they are actually healing! The true test is reduced swelling, improved range of motion, speed, flexibility, AND physically healthier joint tissue. Use pain blockers wisely and only as needed.

Questions: To further help you, we will need some answers (adjust for species).
o WHERE is the the problem?
o How bad are they (on a scale of 1 to 5, with 5 being unbearable)
o How old (age)?
o Size (height & weight)?

o Under what type of circumstances does the problem happen?
o Is it repeatable and consistently happening, or just occasionally?

o How is the body being used? casual, athletic, working (specifics)
o How often is that joint (area) being used? (An athlete working out and competing will often need more support than someone only occasionally exercising, verses someone that never stretches or works out).

o For horses: How often are you having her trimmed? How is (s)he trimmed? Anything special? Shoed – or barefoot?

o For people: what type of shoes are most often worn during a normal week? How much time is spent sitting (car, home, office)?

o Any x-rays or ultra sound on the afflicted joint(s)?
o Anything unique or abnormal about the affected area?
o Any other medication or treatments, or supplements, tried?
o Any other details or points you think might be important?

MD’s Choice products are PURE NUTRITION… working the right way, in a safe and healthy way, using in forms the body can readily benefit from. They are NOT a ‘quick fix’ in most cases. If drugs aren’t used, it usually takes weeks for most bodies to start noticing a positive difference (unless it is just synovial fluid, and even that can take days to weeks).

It’s our job to help make sure our product is likely to help… and to assist in figuring out the best starting dose and rational expectations for YOUR unique situation (and need). The more information we have, the better we can help you (or determine our product(s) might not help you… or what other medication or treatment(s) you might want to talk with your doctor about, to help accomplish your goals within your budget of either time or money).

Please feel free to answer the above questions (or have the answers ready when you call in), and we’ll try to help you the best we can.
MD’s Choice is the only supplement company that provides PURE Nutrition (no herbs) with the most important human-grade nutrients and offers guaranteed results or your money back that isn’t limited to 1 container, 30 days, or some hoop jump set of impossibilities many of our competitors employ.
We use the products ourselves, our family & friends use these products. MD’s Choice sincerely cares about the quality, consistency, safety, effectiveness, and function of our products. We hope all this matters to you, and are thankful for the 90+% of people that honestly try our product for 3 containers who notice the difference, and become part of the MD’s Choice family of happy customers!
IF you still have questions, feel free to send us a message or give us a call M-F 10am to 6pm E S T (7am to 3pm Pacific Time, though there is usually someone around most weekdays until at least 5pm PST/8pm EST).

  • To Find a Reseller Near You, Please Call Us
  • M-F, 10am to 6pm, Eastern Time, at 1-865-380-0950
  • or send us an email at:

Proper Dosing is important to us, and dosing can vary, depending on a few individual factors: age, weight, height, location (of problem), severity, other medication & medically recommended treatment, goals, and care. If the use is helping supplement nutritional needs, or the problems are moderate, effective dosing is on the label. However, IF there are more serious issues, and pain/or is evident, PLEASE CONSULT YOUR DOCTOR or CALL US FOR OPTIMUM DOSING.

Quality & Service are our chosen specialties

Since 1995, MD's Choice has maintained the very best guarantee in the nutritional supplement market, bar none;  with over a 90% success rate for those that actually use the MD’s Choice products as directed.

An unheard of commitment in the health industry. Our guarantee covers the initial period of use, usually 6 to 24 weeks, depending on the problem, not just 1 bottle, or 30 days, the majority of our competitors have.

For serious problems, please contact us directly for the most effective dosing for the specific body and situation. We want our product to work for you, and believe YOU WILL POSITIVELY SEE RESULTS or GET A FULL REFUND for the containers you purchased (limit 3 large containers). No formal testing (or doctors note) is required for reimbursement (as some of our competitors have).

Our company stands behind our product, because the science is solid, and we have a results based guarantee you can honestly trust! MD’s Choice has had zero complaints with the BBB for over 20 years, and either A+ or 'unrated' (because we don't pay for ratings); something few businesses of any type can brag about, especially businesses in the nutrition or health industries.
For individual consultation or questions about our products, call

Monday - Friday, 10am to 6pm, Eastern Time
or via email at:
(where the -at- becomes the @ symbol, like a normal email) 

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Science, especially nutrition, is a vital part of life... living... and longevity. Nothing on this website, or any other, should ever be given more power or authority than your actual doctor: that has seen the body, ran the tests, poked, prodded, x-rayed or ultra-sounded when necessary, thoroughly examined, and genuinely evaluated the history of the patient. Part of the reason the FDA has regulations and requirements, such as “These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent disease.” is to help protect the consumer from false claims, 'magic cures,' 'miracle claims,' and dangerously avoidable contraindications (side-effects). We understand and agree!

Drugs should have quality control regulations, safety requirements, and that includes all plant derived drugs (herbs) which have their place, but seldom ever in a 'daily supplement, intended for prolonged use.'  Supplements should be tested for all the common contaminants, including heavy metals, which MD's Choice has been doing since the very beginning.

Nutrition is key, good nutrition important, but even the best nutrition doesn't replace the hands on experience of doctors able to evaluate the individual on a case-by-case basis. There are far too many ailments, types of diseases, genetic issues, contributing factors, and medical issues producing side-effects and symptoms for any responsible person - especially a doctor or healthcare related professional - to do more than generalize or suggest some elevated or minimized concern, without in-person testing and a real world exam.

Our products are great, and have had the best Results Based Guarantee in the nutritional industry for over 23 years, which should tell you a whole lot about us and how we do business. WE CARE... If you have a serious concern, or life threatening situation, PLEASE CONSULT YOUR DOCTOR, or a specialist that can see the body, do the tests, and evaluate the individual situation.   Our Privacy Policy